병풀추출물

 

 

GOTU KOLA EXTRACT/CENTELLA ASIATICA

병풀추출물

KOSHER / HALAL / USDA ORGANIC

화장품원료

건강식품원료

 

 

 

 1. Centella Asiatica Extract Overview

 

Where to buy Centella Asiatica Extract Powder with lowering Centella Asiatica Extract price and high quality?

Where to find good information of Wholesale Centella Asiatica Extract and Purchase Centella Asiatica Extract for sales?

As the professional Centella Asiatica Extract manufacturer, Plamed is your best choice.

Centella Asiatica Extract, also named Gotu Kola Extract, is triterpenes containing a variety of α-amyrin.

Its main active ingredients are Asiatic Acid and Asiaticoside. Both of them belong to triterpenoid saponins.

They come from dry grass of centella asiatica. Asiatic Acid in Centella Asiatica Extract has antibacterial

and anti-inflammatory activities. It has inhibitory effect on many kinds of bacteria. Asiatic Acid and

Asiaticoside can promote wound healing, and can be used to repair skin scars.

Centella Asiatica Extract can accelerate the synthesis of fibroblasts and collagen.

It can reduce skin hardness, improve skin nutrition, and facilitate skin metabolism.

Asiaticoside can effectively inhibit melanin activity and dilute pigmentation.

As an “all-rounder”, Centella Asiatica Extract can be used in scar repair, anti-acne, anti-allergy,

whitening and anti-oxidant cosmetics and hair shampoo.

Plamed Centella Asiatica Extract has different specifications. All of them belong to cosmetic grade.

 

 

 

Product NameCAS NumberINCI Name
Centella Asiatica Extract84696-21-9CENTELLA ASIATICA EXTRACT
Product IDSpecificationAppearanceSoluble in
PMQD080170% Total Triterpenes

 

(Asiaticoside + Madecassoside + Asiaticoside B)

Pale yellow to off white powderWater, alcohol
PMQD080210% Total Triterpenes

 

(Asiaticoside + Madecassoside + Asiaticoside B)

Off white powderWater
PMQD080695% AsiaticosideWhite powderAlcohol
PMQD080390% Madecassoside

 

(Madecassoside + Asiaticoside B)

White powderWater
PMQD080536-44% Asiaticoside (HPLC), 54-66% Asiatic acid + Madecassic acid (titration)Off white powderAlcohol

 

 

 2. Centella Asiatica Extract Source

Centella asiatica, also called gotu kola, centella, is a perennial creeping herb.

Centella asiatica is native to India. It is widely distributed in the tropical

and subtropical regions of the world. It is mainly distributed in south of the

Yangtze river of China. Centella asiatica prefers to grow on wet river banks,

swamps and meadows. It has been used as medicine in China for more than 2,000 years.

Many other countries and regions, such as Madagascar, South Africa, India,

southeast Asian countries and South America, also use it as auxiliary medicine and

dermatologic medicine. The main active ingredients used in cosmetics are asiatic acid

and madecassic acid, asiaticoside and madecassoside.

 

 

 

 

 

 SPECIFICATION

Product NameSpecificationColor
Centella Asiatica Extract70% Total Triterpenes

 

(Asiaticoside + Madecassoside + Asiaticoside B)

Pale yellow to off white powder
10% Total Triterpenes

 

(Asiaticoside + Madecassoside + Asiaticoside B)

Off white powder
95% AsiaticosideWhite powder
90% Madecassoside

 

(Madecassoside + Asiaticoside B)

White powder
36-44% Asiaticoside  (HPLC), 54-66% Asiatic acid + Madecassic acid (titration)Off-white powder

 

 

Total Triterpenes 70% (water-soluble) Specification

ItemsSpecifications
AssayTotal triterpenes≥70.0%
AppearanceLight yellow powder
TLCConforms
Physical Characteristics
Loss drying≤3.0%
Ignition residue<1.0%
Solubility1g dissolved in 50ml water
Granule size98% though 80 mesh
Heavy Metals
Heavy metals<20ppm
Pb<0.5ppm
Hg<0.05ppm
Cu<5.0ppm
Total Bacterial Count
Yeast/moulds≤1000CFU/G
Salmonella≤100CFU/G
E-CoilNegative

 

 Asiaticoside 36-44%(HPLC), Asiatic Acid+ Madecassic 54-66%(Titration)Specification

ItemsSpecifications
AssayAsiaticoside :36-44%(HPLC)

 

Madecassic& Asiatic acid:54-66%( Titration)

AppearanceWhite powder
TLCConforms
Physical Characteristics
Loss drying≤3.0%
Ignition residue<1.0%
Granule size98% though 100 mesh
Heavy Metals
Heavy metals<20ppm
Pb<0.5ppm
Hg<0.05ppm
Cu<5.0ppm
Total Bacterial Count
Yeast/moulds≤1000CFU/G
Salmonella≤100CFU/G
E-CoilNegative

 

 

 4. Centella Asiatica Extract Manufacturer Process Flow Chart


 

 

5. Centella Asiatica Extract Benefits

Anti-bacterial and anti-inflammation

Centella Asiatica Extract has a certain inhibitory effect on pseudomonas aeruginosa, staphylococcus aureus and acne bacillus.

Asiatic acid can dissolve the bacteria’s outer waxy membranes and is killed by other drugs or body defense tissues.

Asiatic acid and asiaticoside are available for external use to promote wound healing, and stimulate the development of granulation tissue.

It can promote cutin or epidermal regeneration. It helps to form connective tissue.

It is better to use with phospholipids. Centella Asiatica Extract has obvious effect of eliminating facial whelk and acne.

Centella Asiatica Extract can reduce the production of pro-inflammatory mediators (IL-1, MMP-1). It improves

and repairs the skin’s barrier function. Thereby it can prevent and correct the skin’s immune dysfunction.

Therefore, Centella Asiatica Extract, due to its anti-inflammatory activity, can also be used in cosmetics

such as after-sun repair and anti-allergic products.

 

Whitening

Centella Asiatica Extract also has strong antioxidant effect. It can inhibit free radical activity,

and weaken melanin pigmentation. It improves skin blood circulation, and updates skin cell regeneration.

Also it helps melanin metabolize out of the body smoothly. Skin will become smooth, delicate

and white after using cosmetics containing Centella Asiatica Extract.

 

Repairing scars

Scientific research has found that Centella Asiatica Extract can promote the synthesis of collagen Ⅰ and Ⅲ.

At the same time, it also can promote mucoitin secretion (such as the synthesis of hyaluronic acid);

it increases skin moisture-retaining ability; it activates and renews skin cells. Other studies have showed

that Centella Asiatica Extract also can activate fibroblast gene. It can enhance the activity of the basal layer cells of the skin;

it maintains the elasticity and tightness of skin; and it smoothes fine wrinkles of face.

Because of its important role in promoting collagen synthesis, angiogenesis and granulation growth in the body,

Centella Asiatica Extract is conducive to wound healing, scar repair. It prevents striae gravidarum during pregnancy.

 

 

 

 

 6. Pharmacological Study of Centella Asiatica Extract and Cosmetics

Test ItemConcentrationResult
Promotion effect of asiaticoside on the proliferation of human keratinocytes100ug/mLPromotion rate:116.1(blank 100)
Promotion effect of asiaticoside on the proliferation of human fibroblasts50ug/mLPromotion rate:127.1(blank 100)
Promotion effect of asiatic acid on collagen production10umol/LPromotion rate:150 (blank 100)
Promotion effect of asiaticoside on collagen production10umol/LPromotion rate: 255(blank 100)
Inhibitory effect of asiaticoside on the activity of scar fibroblasts0.5mg/mLInhibition rate: 59.7%
Inhibitory effect of asiaticoside on ear swelling in mice0.5umol each ear

Inhibition rate: 45.1%

 

 

 7. Plamed Centella Asiatica Extract Characteristic

> Complete in specifications. Plamed has water-solubility and non water-solubility
> Centella Asiatica Extract. It can be used in cosmetics of different textures.
> Select high quality Centella Asiatica as raw material.

 

 

 

 8. Centella Asiatica Extract Application and Reference Dosage

Centella Asiatica Extract has many skin-care bioactivities.

So it can be used in whitening, anti-oxidation, removing acne, anti-inflammation and scar repair cosmetics.

Centella Asiatica Extract has estrogen-like effect. It can stimulate the growth rate of hair.

Thus it can be used in shampoo with dosage of about 0.05%.

 

ProductReference Dosage
Centella Asiatica Extract0.3-1.5%

 

Centella Asiatica Extract application examples in major cosmetic brands around the world:

 

CountryBrandProduct
JapanDr.Ci:LaboMild UV for Sensitive Skin

 

O2 Herbal Gel Oxygen Charge

Melty WinkEye Gel
POLAB.A The Lotion
SwitzerlandLa PrairieLa prairie Skin Caviar Liquid Lift
KoreaAHCHydra Soother Mask

 

Private Real Eye Cream

Sunscreen SPF50+ PA+++

Su:m37Secret Programming Essence

 

Water-Full Rebalancing Gel Lotion

Sunscreen SPF30+ PA+++

MISSHATime Revolution The First Treatment Essence
UASCLINIQUETurnaround Revitalizing Lotion
Estee LauderNutritious Radiant Vitality Energy Lotion Intense Moist

 

Nutritious Rosy Prism Radiant Gel Emulsion

MentholatumAcnes Medicated Powder Lotion
ArtistryEssentials Replenishing Eye Creme
FranceGUERLAINOrchidee Imperiale Exceptional Complete Care The Cream
LOREALRevitalift  anti-wrinkle and firming day cream

 

Revitalift Eye Cream

CetaphilRich Hydrating Night Cream
ChinaWinonaAnti-redness Rich Moisturizing Cream

 

Arbutin whitening and moisturizing cream

PechoinSunscreen SPF30+PA+++
INOHERBRhodiola Fine Whitening and Anti-oxidation Cleansing Foam
Mask FamilyCherry Deep Hydrating Silk Mask
HerboristPurifying Mask Infused With Ferment Filtrate
FRANICAloe Vera Gel

 

 

 9. Centella Asiatica Extract Reference Formula

Wound healing oil:

IngredientContent(%)IngredientContent(%)
Centella Asiatica Extract0.75Methylparaben0.3
Vaseline25.0Fragrance0.3
Lanolin35.0WaterAdd to 100
Liquid paraffin22

Whitening emulsion:

IngredientContent(%)IngredientContent(%)
Centella Asiatica Extract2.0Solid paraffin5
Beewax10.0Butylparaben0.4
Liquid paraffin4.0Sodium hydroxide0.1
Glycerol monostearate7.0Borax0.2
Polyoxyethylene sorbitan ether (20) mono-laurate2.0FragranceAppropriate
Placental extract1.0WaterAppropriate

Essence:

IngredientContentIngredientContent
Centella Asiatica Extract10%Hydrola45%
Vitamin E1%Pomegranate extract17%
Lavender essential oil6 dropsRed ginseng extract10%
Rosewood essential oil4 dropsRose essential oil3drops
Phospholipids PMB0.5%PMA(thickener)1%
Hyaluronic acid10%Olive oil(solubilizer)2%
Hemp-seed oil1%Pomelo seed extract1%
Mink oil1%  

Preparation method:

Mix the oil phase ingredients (hemp seed oil, mink oil, vitamin E and various essential oils),

thickener and solubilizer evenly, then add water phase ingredients into oil phase, and stir well.

Rose essential oil has good permeability and fusion. It can stimulate various metabolic reactions of skin cells,

and activate cell regeneration ability. Also it inhibits oxygen free radical activity and controls tyrosinase oxidation.

It has anti-spot anti-aging effect, and helps the skin to absorb other components.

Whitening lotion:

IngredientContent(%)IngredientContent(%)
Centella Asiatica Extract6Angelica Root Extract8
Rose flower extract1Pueraria Extract3
Platycodon extract4Aloe Vera Extract10
Pearl powder5Artemisia Capillaris Extract2
Glycyrrhiza Glabra extract8Papain1
Vitamin E oil6Vitamin B61
Distilled water40

 

Preparation method:

Mix evenly ingredients except Pearl powder, Papain, Vitamin E oil and Vitamin B6.

Heat to 50°C for 40-60min. Stir well and cool to room temperature naturally.

Then add rest ingredients and use Ultrasonic vibration for 10-20min, then get the lotion.

 

Cuticle repair toner:

 IngredientContent(%)IngredientContent(%)
Skin conditionerCentella Asiatica Extract3Chamomile extract1
Althaea officinalis root extract1
Flower waterVerbena flower water10Citrus aurantium amara flower water5
Lavender water59.7
Humectant1,3- propylene glycol71,3- pentanediol0.5
Xylitol3Fucogel-10.5
Sodium hyaluronate0.02Glycerin2
PreservativeGlucolactone0.7
Deionized waterAdd to 100

 

Preparation method:

 

> Add the humectants and deionized water to agitator kettle, heat to 60-80°C, stir and mix evenly.

> Cool to 35-45°C, then add Flower water and Skin conditioners, stir well until dissolved completely.

> Add preservative and stir until well combined.

> Check the sample, and filtrate after it is qualified. Ph value should be controlled at 5-7.

 

Moisturizing lotion:

IngredientContent(%)IngredientContent(%)
Centella Asiatica Extract3Angelica Root Extract10
Passiflora extract4Pueraria Extract5
Platycodon extract1Aloe vera extract16
Ginseng extract1Squalane10
Papain1Olive oil5
Vitamin B63Ginkgo biloba extract5
Walnut oil3Distilled water30

 

Preparation method:

Mix evenly ingredients except Squalane, Papain, Olive oil and Vitamin B6.

Heat to 50°C for 40-60min. Stir well and cool to room temperature naturally.

Then add rest ingredients and use Ultrasonic vibration for 10-20min, then get the lotion.

 

 

 10. Centella Asiatica Extract Safety

> CAFFCI and CFDA both recognize CENTELLA ASIATICA EXTRACT as cosmetic raw material.

> CTFAhas specified CENTELLA ASIATICA EXTRACT as a raw material for cosmetics.

> CENTELLA ASIATICA EXTRACTis listed in The List of Used Cosmetic Ingredient approved

by the Ministry of Health of the People’s Republic of China in 2001.

 

 

 

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